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Importantly, these receptors have been found to are already activated by an array of endogenous opioids in a focus similar to that observed for activation and signaling of classical opiate receptors. Subsequently, these receptors were uncovered to possess scavenging action, binding to and lowering endogenous levels of opiates readily available for

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Importantly, these receptors ended up found to have been activated by an array of endogenous opioids in a concentration much like that observed for activation and signaling of classical opiate receptors. In turn, these receptors were being found to have scavenging exercise, binding to and lowering endogenous levels of opiates readily available for

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Researchers have recently recognized and succeeded in synthesizing conolidine, a pure compound that shows promise for a strong analgesic agent with a far more favorable protection profile. Although the specific mechanism of action remains elusive, it can be currently postulated that conolidine may have many biologic targets. Presently, conolidine h

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